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GIPC1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P-Leica, E |
|---|---|
| Primary Accession | O14908 |
| Other Accession | Q9Z254, Q9Z0G0, NP_974199.1, NP_974196.1 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36049 Da |
| Antigen Region | 52-81 aa |
| Gene ID | 10755 |
|---|---|
| Other Names | PDZ domain-containing protein GIPC1, GAIP C-terminus-interacting protein, RGS-GAIP-interacting protein, RGS19-interacting protein 1, Synectin, Tax interaction protein 2, TIP-2, GIPC1, C19orf3, GIPC, RGS19IP1 |
| Target/Specificity | This GIPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human GIPC1. |
| Dilution | WB~~1:2000 IHC-P-Leica~~1:500 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GIPC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GIPC1 |
|---|---|
| Synonyms | C19orf3, GIPC, RGS19IP1 |
| Function | May be involved in G protein-linked signaling. |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
| Tissue Location | Widely expressed (PubMed:9770488). Expressed in skeletal muscle (at protein level) (PubMed:32413282) |
Provided below are standard protocols that you may find useful for product applications.
Background
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Wu, D., et al. J. Biol. Chem. 285(37):28643-28650(2010)
Razanskas, R., et al. Arch. Virol. 155(2):247-250(2010)
Puri, C., et al. Oncogene 29(2):188-200(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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