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Mouse Araf Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P04627 |
| Other Accession | NP_001153117.1, NP_033833.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 67581 Da |
| Antigen Region | 249-277 aa |
| Gene ID | 11836 |
|---|---|
| Other Names | Serine/threonine-protein kinase A-Raf, Proto-oncogene A-Raf, Araf, A-raf, Araf1 |
| Target/Specificity | This Mouse Araf antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of mouse Araf. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Araf Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Araf |
|---|---|
| Synonyms | A-raf, Araf1 |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade (By similarity). Phosphorylates PFKFB2 (By similarity). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Araf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus.
References
Odvody, J., et al. Oncogene 29(22):3287-3296(2010)
Li, Z., et al. PLoS ONE 5 (8), E12181 (2010) :
Provot, S., et al. Mol. Cell. Biol. 28(1):344-357(2008)
Yokoyama, T., et al. J. Cell Biol. 177(5):781-793(2007)
Gerits, N., et al. Transgenic Res. 16(3):281-314(2007)
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