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PTHD2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9P2K9 |
| Other Accession | NP_065831.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 153048 Da |
| Antigen Region | 179-207 aa |
| Gene ID | 57540 |
|---|---|
| Other Names | Patched domain-containing protein 2, Protein dispatched homolog 3, PTCHD2, DISP3, KIAA1337 |
| Target/Specificity | This PTHD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human PTHD2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PTHD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DISP3 {ECO:0000303|PubMed:15645143, ECO:0000312|HGNC:HGNC:29251} |
|---|---|
| Function | Plays a role in neuronal proliferation and differentiation (PubMed:25281927). Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation (PubMed:25281927). May contribute to cholesterol homeostasis in neuronal cells (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:B9U3F2}; Multi-pass membrane protein. Note=Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity) {ECO:0000250|UniProtKB:B9U3F2, ECO:0000269|PubMed:19179482} |
| Tissue Location | Expressed in brain and testis (PubMed:15645143). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Peart, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 102(10):3697-3702(2005)
Katoh, Y., et al. Int. J. Oncol. 26(2):551-556(2005)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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