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GALR3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O60755 |
| Other Accession | O88626, O88853, NP_003605.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39573 Da |
| Antigen Region | 279-307 aa |
| Gene ID | 8484 |
|---|---|
| Other Names | Galanin receptor type 3, GAL3-R, GALR-3, GALR3, GALNR3 |
| Target/Specificity | This GALR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-307 amino acids from the C-terminal region of human GALR3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GALR3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GALR3 |
|---|---|
| Synonyms | GALNR3 |
| Function | Receptor for the hormone galanin (PubMed:25691535). Receptor for the hormone spexin-1 (PubMed:24517231). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Provided below are standard protocols that you may find useful for product applications.
Background
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts
References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
Belfer, I., et al. Genes Brain Behav. 6(5):473-481(2007)
Berger, A., et al. Neuroendocrinology 75(2):130-138(2002)
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