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CAPN13 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6MZZ7 |
| Other Accession | Q3UW68, NP_653176.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 76696 Da |
| Antigen Region | 537-565 aa |
| Gene ID | 92291 |
|---|---|
| Other Names | Calpain-13, 3422-, Calcium-activated neutral proteinase 13, CANP 13, CAPN13 |
| Target/Specificity | This CAPN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human CAPN13. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CAPN13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CAPN13 |
|---|---|
| Function | Probable non-lysosomal thiol-protease. |
| Tissue Location | Weakly expressed in lung and testis. Weakly or not expressed in other tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN13 belongs to the calpain large subunit family.
References
Taylor, J.Y., et al. Biol Res Nurs 12(2):149-155(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Dear, T.N., et al. Gene 274 (1-2), 245-252 (2001) :
Dear, T.N., et al. Genomics 68(2):152-160(2000)
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