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CEACAM8 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P31997 |
| Other Accession | NP_001807.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38154 Da |
| Antigen Region | 53-81 aa |
| Gene ID | 1088 |
|---|---|
| Other Names | Carcinoembryonic antigen-related cell adhesion molecule 8, CD67 antigen, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, CD66b, CEACAM8, CGM6 |
| Target/Specificity | This CEACAM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the N-terminal region of human CEACAM8. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CEACAM8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CEACAM8 |
|---|---|
| Synonyms | CGM6 |
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. Cell surface |
| Tissue Location | Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Lasa, A., et al. Ann. Hematol. 87(3):205-211(2008)
Skubitz, K.M., et al. J Transl Med 6, 78 (2008) :
Yoon, J., et al. J. Immunol. 179(12):8454-8462(2007)
Ordonez, C., et al. J. Cell. Physiol. 210(3):757-765(2007)
Ramachandran, P., et al. J. Proteome Res. 5(6):1493-1503(2006)
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