UBE2Q2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8WVN8 |
Other Accession | Q8K2Z8, Q32L27, NP_775740.1, NP_001138807.1 |
Reactivity | Human |
Predicted | Bovine, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 42818 Da |
Antigen Region | 168-196 aa |
Gene ID | 92912 |
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Other Names | Ubiquitin-conjugating enzyme E2 Q2, Ubiquitin carrier protein Q2, Ubiquitin-protein ligase Q2, UBE2Q2 |
Target/Specificity | This UBE2Q2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the Central region of human UBE2Q2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | UBE2Q2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UBE2Q2 |
---|---|
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. |
Cellular Location | Cytoplasm. |
Tissue Location | Detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium |
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Provided below are standard protocols that you may find useful for product applications.
Background
UBE2Q2 accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination.
References
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Nikseresht, M., et al. Cancer Genet. Cytogenet. 197(2):101-106(2010)
Maeda, H., et al. Mol. Cancer Res. 7(9):1553-1562(2009)
Banerjee, S., et al. Oncogene 26(45):6509-6517(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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