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TMEM5 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y2B1 |
| Other Accession | NP_055069.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51146 Da |
| Antigen Region | 55-82 aa |
| Gene ID | 10329 |
|---|---|
| Other Names | Transmembrane protein 5, TMEM5 |
| Target/Specificity | This TMEM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-82 amino acids from the N-terminal region of human TMEM5. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TMEM5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RXYLT1 (HGNC:13530) |
|---|---|
| Synonyms | TMEM5 |
| Function | Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4- xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O- mannosyl glycan (Probable) (PubMed:27733679, PubMed:29477842). Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4- (phosphate-6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (Probable) (PubMed:25279699, PubMed:27601598, PubMed:27733679). |
| Cellular Location | Golgi apparatus membrane; Single-pass type II membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TMEM5 is a putative type II membrane protein.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Yokoyama-Kobayashi, M., et al. Gene 228 (1-2), 161-167 (1999) :
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