TMEM5 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9Y2B1 |
Other Accession | NP_055069.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 51146 Da |
Antigen Region | 55-82 aa |
Gene ID | 10329 |
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Other Names | Transmembrane protein 5, TMEM5 |
Target/Specificity | This TMEM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-82 amino acids from the N-terminal region of human TMEM5. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TMEM5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RXYLT1 (HGNC:13530) |
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Synonyms | TMEM5 |
Function | Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4- xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O- mannosyl glycan (PubMed:27733679, PubMed:29477842) (Probable). Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4- (phosphate-6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:27601598, PubMed:27733679) (Probable). |
Cellular Location | Golgi apparatus membrane; Single-pass type II membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
TMEM5 is a putative type II membrane protein.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Yokoyama-Kobayashi, M., et al. Gene 228 (1-2), 161-167 (1999) :
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