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TEKT1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q969V4 |
| Other Accession | NP_444515.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48283 Da |
| Antigen Region | 252-281 aa |
| Gene ID | 83659 |
|---|---|
| Other Names | Tektin-1, TEKT1 |
| Target/Specificity | This TEKT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human TEKT1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TEKT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TEKT1 |
|---|---|
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q32KZ9} |
| Tissue Location | Predominantly expressed in testis. Expressed in airway epithelial cells (PubMed:36191189) |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis.
References
Newby, P.R., et al. Eur. J. Hum. Genet. 18(9):1021-1026(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Iguchi, N., et al. Mol. Hum. Reprod. 8(6):525-530(2002)
Xu, M., et al. Int. J. Biochem. Cell Biol. 33(12):1172-1182(2001)
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