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GREB1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q4ZG55 |
| Other Accession | Q3UHK3, NP_055483.2, NP_149081.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 216467 Da |
| Antigen Region | 1417-1446 aa |
| Gene ID | 9687 |
|---|---|
| Other Names | Protein GREB1, Gene regulated in breast cancer 1 protein, GREB1, KIAA0575 |
| Target/Specificity | This GREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1417-1446 amino acids from the Central region of human GREB1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GREB1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GREB1 |
|---|---|
| Synonyms | KIAA0575 |
| Function | May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers. |
| Cellular Location | Membrane; Single-pass membrane protein |
| Tissue Location | Expressed in proliferating prostatic tissue and prostate cancer. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq].
References
Hnatyszyn, H.J., et al. Breast Cancer Res. Treat. 122(2):371-380(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Rittie, L., et al. Arch Dermatol 144(9):1129-1140(2008)
Sun, J., et al. Mol. Endocrinol. 21(11):2651-2662(2007)
Deschenes, J., et al. J. Biol. Chem. 282(24):17335-17339(2007)
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