MEX3B Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q6ZN04 |
Other Accession | Q69Z36, NP_115622.2 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 58832 Da |
Antigen Region | 37-65 aa |
Gene ID | 84206 |
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Other Names | RNA-binding protein MEX3B, RING finger and KH domain-containing protein 3, RING finger protein 195, MEX3B, KIAA2009, RKHD3, RNF195 |
Target/Specificity | This MEX3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human MEX3B. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MEX3B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MEX3B |
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Synonyms | KIAA2009, RKHD3, RNF195 |
Function | RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms. |
Cellular Location | Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3- 3 |
Tissue Location | Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level. |
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Provided below are standard protocols that you may find useful for product applications.
Background
RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.
References
Nicolas, E., et al. Eur. J. Hum. Genet. 18(10):1107-1113(2010)
Willer, C.J., et al. Nat. Genet. 41(1):25-34(2009)
Courchet, J., et al. J. Biol. Chem. 283(46):32131-32142(2008)
Buchet-Poyau, K., et al. Nucleic Acids Res. 35(4):1289-1300(2007)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
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