SF4 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q8IWZ8 |
| Other Accession | Q68FU8, Q8CH02, NP_757386.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 72471 Da |
| Antigen Region | 364-393 aa |
| Gene ID | 57794 |
|---|---|
| Other Names | SURP and G-patch domain-containing protein 1, RNA-binding protein RBP, Splicing factor 4, SUGP1, SF4 |
| Target/Specificity | This SF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the Central region of human SF4. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SF4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SUGP1 |
|---|---|
| Synonyms | SF4 |
| Function | Plays a role in pre-mRNA splicing. |
| Cellular Location | Nucleus. |
| Tissue Location | Detected in adult testis and heart, and in adult and fetal brain, kidney and skeletal muscle |

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Provided below are standard protocols that you may find useful for product applications.
Background
SF4 is a member of the SURP family of splicing factors.
References
Hegele, R.A., et al. Hum. Mol. Genet. 18(21):4189-4194(2009)
Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Sampson, N.D., et al. Gene 305(1):91-100(2003)
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