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CCL27 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y4X3 |
| Other Accession | NP_006655.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 12618 Da |
| Antigen Region | 74-102 aa |
| Gene ID | 10850 |
|---|---|
| Other Names | C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27, CCL27, ILC, SCYA27 |
| Target/Specificity | This CCL27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the C-terminal region of human CCL27. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CCL27 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCL27 |
|---|---|
| Synonyms | ILC, SCYA27 |
| Function | Chemotactic factor that attracts skin-associated memory T- lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:Q9Z1X0}. |
| Tissue Location | Testis, thymus, placenta, ovary and skin. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)
Narbutt, J., et al. Mediators Inflamm. 2009, 269541 (2009) :
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