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KRR1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q13601 |
| Other Accession | NP_008974.5 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43665 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 11103 |
|---|---|
| Other Names | KRR1 small subunit processome component homolog, HIV-1 Rev-binding protein 2, KRR-R motif-containing protein 1, Rev-interacting protein 1, Rip-1, KRR1, HRB2 |
| Target/Specificity | This KRR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KRR1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KRR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRR1 (HGNC:5176) |
|---|---|
| Synonyms | HRB2 |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. |
| Cellular Location | Nucleus, nucleolus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).
References
Bailey, S.D., et al. Diabetes Care (2010) In press : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Olsen, J.V., et al. Cell 127(3):635-648(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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