TRAT1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q6PIZ9 |
Other Accession | NP_057472.2 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 21211 Da |
Antigen Region | 98-127 aa |
Gene ID | 50852 |
---|---|
Other Names | T-cell receptor-associated transmembrane adapter 1, T-cell receptor-interacting molecule, TRIM, pp29/30, TRAT1, TCRIM |
Target/Specificity | This TRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the Central region of human TRAT1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TRAT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TRAT1 |
---|---|
Synonyms | TCRIM |
Function | Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. |
Cellular Location | Cell membrane; Single-pass type III membrane protein |
Tissue Location | Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
TRAT1 stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
References
Jarvis, L.B., et al. Hum. Immunol. 69(11):687-695(2008)
Tedoldi, S., et al. Blood 107(1):213-221(2006)
Koyasu, S. Nat. Immunol. 4(4):313-319(2003)
Kirchgessner, H., et al. J. Exp. Med. 193(11):1269-1284(2001)
Zhang, W., et al. Semin. Immunol. 12(1):35-41(2000)
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