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> home > Products > Primary Antibodies > Antibody Collections > Ubiquitin E3 Ligases (RING Domain) Antibodies > TRIM46 Antibody (N-term)
TRIM46 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q7Z4K8 |
| Other Accession | Q7TNM2, NP_079334.3, A0A0G2JXN2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 83424 Da |
| Antigen Region | 75-104 aa |
| Gene ID | 80128 |
|---|---|
| Other Names | Tripartite motif-containing protein 46, Gene Y protein, GeneY, Tripartite, fibronectin type-III and C-terminal SPRY motif protein, TRIM46, TRIFIC |
| Target/Specificity | This TRIM46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human TRIM46. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRIM46 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRIM46 |
|---|---|
| Synonyms | TRIFIC |
| Function | Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration. |
| Cellular Location | Cell projection, axon {ECO:0000250|UniProtKB:Q7TNM2}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q7TNM2}. Note=Microtubule-associated. Localizes to the proximal part of the axon. {ECO:0000250|UniProtKB:Q7TNM2} |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the TRIM/RBCC family. There are 4 isoforms of this protein.
References
Short, K.M., et al. J. Biol. Chem. 281(13):8970-8980(2006)
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$ 182.50
$ 70.00
Cat# AP17174A
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