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ZKSCAN1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P17029 |
| Other Accession | NP_003430.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 63630 Da |
| Antigen Region | 238-265 aa |
| Gene ID | 7586 |
|---|---|
| Other Names | Zinc finger protein with KRAB and SCAN domains 1, Zinc finger protein 139, Zinc finger protein 36, Zinc finger protein KOX18, ZKSCAN1, KOX18, ZNF139, ZNF36 |
| Target/Specificity | This ZKSCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-265 amino acids from the Central region of human ZKSCAN1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZKSCAN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZKSCAN1 |
|---|---|
| Synonyms | KOX18, ZNF139, ZNF36 |
| Function | May be involved in transcriptional regulation. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM].
References
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Jikuya, H., et al. DNA Res. 10(1):49-57(2003)
Tommerup, N., et al. Genomics 27(2):259-264(1995)
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