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MCAT Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IVS2 |
| Other Accession | NP_775738.3, NP_055322.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42962 Da |
| Antigen Region | 316-344 aa |
| Gene ID | 27349 |
|---|---|
| Other Names | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial, MCT, Mitochondrial malonyl CoA:ACP acyltransferase, Mitochondrial malonyltransferase, [Acyl-carrier-protein] malonyltransferase, MCAT, MT |
| Target/Specificity | This MCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-344 amino acids from the C-terminal region of human MCAT. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MCAT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MCAT (HGNC:29622) |
|---|---|
| Synonyms | MT |
| Function | Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondria. |
| Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Two transcript variants encoding different isoforms have been found for this gene.
References
Kim, S.T., et al. Prostate 70(16):1729-1738(2010)
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Ma, J., et al. Atherosclerosis 191(1):63-72(2007)
Kuhl, J.E., et al. Am. J. Physiol. Endocrinol. Metab. 290 (6), E1296-E1303 (2006) :
Zhang, L., et al. J. Biol. Chem. 278(41):40067-40074(2003)
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