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UNKL Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H9P5 |
| Other Accession | Q5FWH2, NP_001180317.1, NP_001032202.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73828 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 64718 |
|---|---|
| Other Names | Putative E3 ubiquitin-protein ligase UNKL, 632-, RING finger protein unkempt-like, Zinc finger CCCH domain-containing protein 5-like, UNKL, C16orf28, ZC3H5L, ZC3HDC5L |
| Target/Specificity | This UNKL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UNKL. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UNKL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UNKL |
|---|---|
| Synonyms | C16orf28, ZC3H5L, ZC3HDC5L |
| Function | May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven. |
| Cellular Location | [Isoform 4]: Cytoplasm. Nucleus. Note=Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
UNKL may participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven.
References
Lores, P., et al. FEBS J. 277(6):1453-1464(2010)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Martin, J., et al. Nature 432(7020):988-994(2004)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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