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RHOT2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IXI1 |
| Other Accession | NP_620124.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 68118 Da |
| Antigen Region | 291-320 aa |
| Gene ID | 89941 |
|---|---|
| Other Names | Mitochondrial Rho GTPase 2, MIRO-2, hMiro-2, 365-, Ras homolog gene family member T2, RHOT2, ARHT2, C16orf39 |
| Target/Specificity | This RHOT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the Central region of human RHOT2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RHOT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RHOT2 |
|---|---|
| Synonyms | ARHT2, C16orf39 |
| Function | Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking (PubMed:16630562, PubMed:22396657, PubMed:30513825). Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (PubMed:22396657). Can hydrolyze GTP (By similarity). Can hydrolyze ATP and UTP (PubMed:30513825). |
| Cellular Location | Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Colocalizes with MGARP and RHOT2 at the mitochondria |
| Tissue Location | Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
References
Saotome, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(52):20728-20733(2008)
Fransson, S., et al. Biochem. Biophys. Res. Commun. 344(2):500-510(2006)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Aspenstrom, P., et al. Biochem. J. 377 (PT 2), 327-337 (2004) :
Shan, Y., et al. Cytogenet. Genome Res. 106(1):91-97(2004)
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