ZNF131 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P52739 |
Other Accession | NP_003423.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 71422 Da |
Antigen Region | 205-233 aa |
Gene ID | 7690 |
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Other Names | Zinc finger protein 131, ZNF131 |
Target/Specificity | This ZNF131 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human ZNF131. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZNF131 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZNF131 |
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Function | Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling. |
Cellular Location | Nucleus Note=Sumoylation does not affect nuclear localization |
Tissue Location | Predominant expression is found in different brain areas such as the occipital and temporal lobe, the nucleus caudatus, hippocampus, and the cerebellum as well as in testis and thymus |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF131 may be involved in transcriptional regulation. Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity).
References
Han, X., et al. BMC Genomics 9, 476 (2008) :
Donaldson, N.S., et al. Biochim. Biophys. Acta 1773(4):546-555(2007)
Schmutz, J., et al. Nature 431(7006):268-274(2004)
Trappe, R., et al. Biochem. Biophys. Res. Commun. 296(2):319-327(2002)
Tommerup, N., et al. Genomics 27(2):259-264(1995)
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