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AGAP3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96P47 |
| Other Accession | Q8VHH5, NP_001036000.1, NP_114152.3 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 95044 Da |
| Antigen Region | 190-217 aa |
| Gene ID | 116988 |
|---|---|
| Other Names | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3, AGAP-3, CRAM-associated GTPase, CRAG, Centaurin-gamma-3, Cnt-g3, MR1-interacting protein, MRIP-1, AGAP3, CENTG3 |
| Target/Specificity | This AGAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-217 amino acids from the N-terminal region of human AGAP3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AGAP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AGAP3 |
|---|---|
| Synonyms | CENTG3 |
| Function | GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway. |
| Cellular Location | Cytoplasm. Note=In cells upon oxidative stress or in brains of Machado-Joseph disease patients, translocates to PML nuclear bodies |
| Tissue Location | Widely expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.
References
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Qin, Q., et al. J. Cell Biol. 172(4):497-504(2006)
Meurer, S., et al. J. Biol. Chem. 279(47):49346-49354(2004)
Surks, H.K., et al. J. Biol. Chem. 278(51):51484-51493(2003)
Xia, C., et al. Mol. Cell. Biol. 23(7):2476-2488(2003)
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