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PDGFRL Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q15198 |
| Other Accession | Q2PFX1, Q5BIP2, NP_006198.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41861 Da |
| Antigen Region | 16-44 aa |
| Gene ID | 5157 |
|---|---|
| Other Names | Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS |
| Target/Specificity | This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human PDGFRL. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PDGFRL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PDGFRL |
|---|---|
| Synonyms | PRLTS |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in colon, lung and liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Guo, F.J., et al. World J. Gastroenterol. 16(12):1465-1472(2010)
Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) :
Xu, M., et al. BMC Genomics 9 SUPPL 1, S12 (2008) :
Seitz, S., et al. Genes Chromosomes Cancer 45(6):612-627(2006)
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