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DACT3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96B18 |
| Other Accession | Q0PHV7, NP_659493.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 64949 Da |
| Antigen Region | 139-165 aa |
| Gene ID | 147906 |
|---|---|
| Other Names | Dapper homolog 3, Antagonist of beta-catenin Dapper homolog 3, Arginine-rich region 1 protein, Dapper antagonist of catenin 3, DACT3, RRR1 |
| Target/Specificity | This DACT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-165 amino acids from the N-terminal region of human DACT3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DACT3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DACT3 |
|---|---|
| Synonyms | RRR1 |
| Function | May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Dact3 is the gene product of the third discovered member of the Dact (Dapper) family of developmentally-expressed genes. Discovered in mouse, a highly conserved ortholog also exists in the human genome. As with other Dact family members, Dact3 may play a role in antagonism of Wnt signaling.
References
Jiang, X., et al. Cancer Cell 13(6):529-541(2008)
Fisher, D.A., et al. Dev. Dyn. 235(9):2620-2630(2006)
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