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EPSTI1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96J88 |
| Other Accession | NP_150280.1, NP_001002264.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36793 Da |
| Antigen Region | 15-41 aa |
| Gene ID | 94240 |
|---|---|
| Other Names | Epithelial-stromal interaction protein 1, EPSTI1 |
| Target/Specificity | This EPSTI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human EPSTI1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EPSTI1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EPSTI1 |
|---|---|
| Function | Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity). |
| Tissue Location | Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
de Neergaard, M., et al. Am. J. Pathol. 176(3):1229-1240(2010)
Nielsen, H.L., et al. Genomics 79(5):703-710(2002)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995) :
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