CCIN Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q13939 |
Other Accession | Q5XI58, Q8CDE2, Q28068, NP_005884.2 |
Reactivity | Human |
Predicted | Bovine, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 66582 Da |
Antigen Region | 373-400 aa |
Gene ID | 881 |
---|---|
Other Names | Calicin, CCIN |
Target/Specificity | This CCIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-400 amino acids from the Central region of human CCIN. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CCIN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCIN |
---|---|
Function | Possible morphogenetic cytoskeletal element in spermiogenic differentiation. |
Cellular Location | Cytoplasm, cytoskeleton, perinuclear theca, calyx. Note=Sperm head cytoskeletal structure tightly associated to the nucleus |
Tissue Location | Testis. Not detectable or shows a drastically altered pattern of arrangement in the heads of malformed spermatozoa |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a basic protein of the sperm head cytoskeleton. This protein contains kelch repeats and a BTB/POZ domain and is necessary for normal morphology during sperm differentiation. This gene is intronless.
References
Lecuyer, C., et al. Biol. Reprod. 63(6):1801-1810(2000)
von Bulow, M., et al. Exp. Cell Res. 219(2):407-413(1995)
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