IKBIP Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q70UQ0 |
Other Accession | NP_963906.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39309 Da |
Antigen Region | 319-345 aa |
Gene ID | 121457 |
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Other Names | Inhibitor of nuclear factor kappa-B kinase-interacting protein, I kappa-B kinase-interacting protein, IKBKB-interacting protein, IKK-interacting protein, IKBIP, IKIP |
Target/Specificity | This IKBIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-345 amino acids from the C-terminal region of human IKBIP. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | IKBIP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IKBIP |
---|---|
Synonyms | IKIP |
Function | Target of p53/TP53 with pro-apoptotic function. |
Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization |
Tissue Location | Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
Target of TP53/p53 with pro-apoptotic function.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hofer-Warbinek, R., et al. Cell Death Differ. 11(12):1317-1325(2004)
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