Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
ZBTB49 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6ZSB9 |
| Other Accession | NP_660334.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 85061 Da |
| Antigen Region | 172-199 aa |
| Gene ID | 166793 |
|---|---|
| Other Names | Zinc finger and BTB domain-containing protein 49, Zinc finger protein 509, ZBTB49, ZNF509 |
| Target/Specificity | This ZBTB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-199 amino acids from the N-terminal region of human ZBTB49. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZBTB49 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZBTB49 |
|---|---|
| Synonyms | ZNF509 |
| Function | Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription. |
| Cellular Location | [Isoform 1]: Cytoplasm. Nucleus Note=Predominantly located in the nucleus |
| Tissue Location | Highly expressed in normal epidermis and in other epithelial tissues, including in colon and lung. Tends to be down- regulated in colon, lung and skin cancer tissues |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
ZBTB49 may be involved in transcriptional regulation.
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
