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ROD1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O95758 |
| Other Accession | Q9Z118, Q8BHD7, NP_001157262.1, NP_005147.3 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 59690 Da |
| Antigen Region | 253-279 aa |
| Gene ID | 9991 |
|---|---|
| Other Names | Polypyrimidine tract-binding protein 3, Regulator of differentiation 1, Rod1, PTBP3, ROD1 |
| Target/Specificity | This ROD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-279 amino acids from the N-terminal region of human ROD1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ROD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PTBP3 |
|---|---|
| Synonyms | ROD1 |
| Function | RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). |
| Tissue Location | Expressed in several hematopoietic cell lines examined. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ROD1 is a functional homolog of nrd1, an S. pombe RNA-binding protein that suppresses the onset of differentiation.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Sadvakassova, G., et al. J. Cell. Physiol. 220(3):672-679(2009)
Yamamoto, H., et al. Mol. Cell. Biol. 19(5):3829-3841(1999)
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