GPR157 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q5UAW9 |
| Other Accession | NP_079256.4 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36623 Da |
| Antigen Region | 178-207 aa |
| Gene ID | 80045 |
|---|---|
| Other Names | Probable G-protein coupled receptor 157, GPR157 |
| Target/Specificity | This GPR157 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human GPR157. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPR157 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR157 |
|---|---|
| Function | Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol- calcium second messenger. |
| Cellular Location | Cell projection, cilium membrane {ECO:0000250|UniProtKB:Q8C206}; Multi-pass membrane protein. Note=Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid {ECO:0000250|UniProtKB:Q8C206} |

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Provided below are standard protocols that you may find useful for product applications.
Background
GPR157 is an orphan receptor.
References
Gregory, S.G., et al. Nature 441(7091):315-321(2006)
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