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SPOCK3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BQ16 |
| Other Accession | Q8BKV0, NP_001035249.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49429 Da |
| Antigen Region | 36-63 aa |
| Gene ID | 50859 |
|---|---|
| Other Names | Testican-3, SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3, SPOCK3, TICN3 |
| Target/Specificity | This SPOCK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of human SPOCK3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SPOCK3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPOCK3 |
|---|---|
| Synonyms | TICN3 |
| Function | May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
| Tissue Location | Expressed in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kamioka, M., et al. Leuk. Res. 33(7):913-918(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Nakada, M., et al. Cancer Res. 61(24):8896-8902(2001)
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