SCLY Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q96I15 |
Other Accession | NP_057594.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 48149 Da |
Antigen Region | 8-36 aa |
Gene ID | 51540 |
---|---|
Other Names | Selenocysteine lyase, hSCL, SCLY, SCL |
Target/Specificity | This SCLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human SCLY. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SCLY Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SCLY |
---|---|
Synonyms | SCL |
Function | Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JLI6} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Yepes, J.O., et al. Biomedica 26(2):194-205(2006)
Mihara, H., et al. J. Biol. Chem. 275(9):6195-6200(2000)
Daher, R., et al. J Trace Elem Electrolytes Health Dis 6(3):189-194(1992)
Esaki, N., et al. J. Biol. Chem. 257(8):4386-4391(1982)
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