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ONECUT3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O60422 |
| Other Accession | Q8K557, NP_001073957.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50037 Da |
| Antigen Region | 393-419 aa |
| Gene ID | 390874 |
|---|---|
| Other Names | One cut domain family member 3, One cut homeobox 3, Transcription factor ONECUT-3, OC-3, ONECUT3 |
| Target/Specificity | This ONECUT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-419 amino acids from the C-terminal region of human ONECUT3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ONECUT3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ONECUT3 |
|---|---|
| Function | Transcriptional activator. Binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00374} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ONECUT3 is transcriptional activator. It binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR (By similarity).
References
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Vanhorenbeeck, V., et al. Biochem. Biophys. Res. Commun. 292(4):848-854(2002)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
Jacquemin, P., et al. J. Biol. Chem. 274(5):2665-2671(1999)
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