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NT5D2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H857 |
| Other Accession | Q6Q0N3, NP_001127703.1 |
| Reactivity | Human |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 60719 Da |
| Antigen Region | 289-317 aa |
| Gene ID | 64943 |
|---|---|
| Other Names | 5'-nucleotidase domain-containing protein 2, 313-, NT5DC2 |
| Target/Specificity | This NT5D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the Central region of human NT5D2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NT5D2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NT5DC2 |
|---|---|
| Function | Promotes dephosphorylation of tyrosine 3-monooxygenase TH which decreases TH catalytic activity and leads to reduced synthesis of catecholamines including dopamine, noradrenaline and adrenaline. The exact mechanism of activity is unknown but may act as a phosphatase or promote the activity of phosphatases or may inhibit phosphorylation by acting as a barrier to interfere with protein kinase access. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q6Q0N3}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
NT5DC2 belongs to the 5'(3')-deoxyribonucleotidase family.
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
Bonaldo, M.F., et al. Genome Res. 6(9):791-806(1996)
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