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ENPP4 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y6X5 |
| Other Accession | A2VDP5, NP_055751.1 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51641 Da |
| Antigen Region | 171-200 aa |
| Gene ID | 22875 |
|---|---|
| Other Names | Bis(5'-adenosyl)-triphosphatase ENPP4, AP3A hydrolase, AP3Aase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 4, E-NPP 4, NPP-4, ENPP4, KIAA0879, NPP4 |
| Target/Specificity | This ENPP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human ENPP4. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ENPP4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ENPP4 |
|---|---|
| Synonyms | KIAA0879, NPP4 |
| Function | Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed on the surface of vascular endothelia. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ENPP4 belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Gijsbers, R., et al. J. Biol. Chem. 276(2):1361-1368(2001)
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