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SGK269 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H792 |
| Other Accession | NP_079052.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 193106 Da |
| Antigen Region | 673-699 aa |
| Gene ID | 79834 |
|---|---|
| Other Names | Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269, PEAK1, KIAA2002 |
| Target/Specificity | This SGK269 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 673-699 amino acids from the N-terminal region of human SGK269. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SGK269 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PEAK1 |
|---|---|
| Synonyms | KIAA2002 |
| Function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:20534451, PubMed:23105102, PubMed:35687021). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell junction, focal adhesion Note=Colocalizes with F-actin in serum-rich medium (PubMed:20534451) Actin colocalization is reduced during serum starvation (PubMed:20534451). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Zody, M.C., et al. Nature 440(7084):671-675(2006)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
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