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LBX1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P52954 |
| Other Accession | Q2PYN8, Q1XID0, P52955, NP_006553.2, Q804R0 |
| Reactivity | Human, Mouse |
| Predicted | Rat, Xenopus, Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 30221 Da |
| Antigen Region | 127-155 aa |
| Gene ID | 10660 |
|---|---|
| Other Names | Transcription factor LBX1, Ladybird homeobox protein homolog 1, LBX1, LBX1H |
| Target/Specificity | This LBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of human LBX1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LBX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LBX1 |
|---|---|
| Synonyms | LBX1H |
| Function | Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.
References
Yu, M., et al. Genes Dev. 23(15):1737-1742(2009)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
de Mollerat, X.J., et al. Hum. Mol. Genet. 12(16):1959-1971(2003)
Kozmik, Z., et al. Genesis 29(4):172-179(2001)
Jagla, K., et al. Mech. Dev. 53(3):345-356(1995)
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