ZNF568 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q3ZCX4 |
| Other Accession | NP_940941.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 74369 Da |
| Antigen Region | 184-211 aa |
| Gene ID | 374900 |
|---|---|
| Other Names | Zinc finger protein 568, ZNF568 |
| Target/Specificity | This ZNF568 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-211 amino acids from the Central region of human ZNF568. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZNF568 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZNF568 |
|---|---|
| Function | Has transcriptional repression activity, partially through the recruitment of the corepressor TRIM28 but also has repression activity independently of this interaction. Essential during embryonic development, where it acts as a direct repressor of a placental- specific transcript of IGF2 in early development and regulates convergent extension movements required for axis elongation and tissue morphogenesis in all germ layers. Also important for normal morphogenesis of extraembryonic tissues including the yolk sac, extraembryonic mesoderm and placenta. May enhance proliferation or maintenance of neural stem cells. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:E9PYI1}. |

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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF568 may be involved in transcriptional regulation (By similarity).
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
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