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NKX6-2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9C056 |
| Other Accession | NP_796374.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29263 Da |
| Antigen Region | 6-2 aa |
| Gene ID | 84504 |
|---|---|
| Other Names | Homeobox protein Nkx-62, Homeobox protein NK-6 homolog B, NKX6-2, GTX, NKX6B |
| Target/Specificity | This NKX6-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human NKX6-2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NKX6-2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NKX6-2 |
|---|---|
| Synonyms | GTX, NKX6B |
| Function | Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA- 3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:D3Z4R4}. |
| Tissue Location | Highest expression in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Lee, S.H., et al. Mamm. Genome 12(2):157-162(2001)
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