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FUT11 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q495W5 |
| Other Accession | NP_775811.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55816 Da |
| Antigen Region | 204-233 aa |
| Gene ID | 170384 |
|---|---|
| Other Names | Alpha-(1, 3)-fucosyltransferase 11, 241-, Fucosyltransferase XI, Fuc-TXI, FucT-XI, Galactoside 3-L-fucosyltransferase 11, Fucosyltransferase 11, FUT11 |
| Target/Specificity | This FUT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from the Central region of human FUT11. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FUT11 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FUT11 {ECO:0000303|PubMed:19088067, ECO:0000312|HGNC:HGNC:19233} |
|---|---|
| Function | Protein O-fucosyltransferase that specifically catalyzes O- fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1 (PubMed:39775168). Attaches fucose through an O-glycosidic linkage (PubMed:39775168). O- fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion (PubMed:39775168). Also shows minor alpha-(1,3)-fucosyltransferase activity toward activity toward biantennary N-glycan acceptors (PubMed:19088067). However, this was tested with a library of synthetic substrates and this activity is unsure in vivo (PubMed:19088067). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Probable fucosyltransferase (By similarity).
References
Mollicone, R., et al. J. Biol. Chem. 284(7):4723-4738(2009)
Roos, C., et al. J. Biol. Chem. 277(5):3168-3175(2002)
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$ 385.00
$ 150.00
Cat# AP18331c
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