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UCK1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HA47 |
| Other Accession | Q4R4K2, NP_113620.1 |
| Reactivity | Human, Mouse |
| Predicted | Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 31435 Da |
| Antigen Region | 231-260 aa |
| Gene ID | 83549 |
|---|---|
| Other Names | Uridine-cytidine kinase 1, UCK 1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1, UCK1, URK1 |
| Target/Specificity | This UCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human UCK1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UCK1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UCK1 |
|---|---|
| Synonyms | URK1 |
| Function | Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:11306702). Does not phosphorylate deoxyribonucleosides or purine ribonucleosides (PubMed:11306702). Can use ATP or GTP as a phosphate donor (PubMed:11306702). Can also phosphorylate cytidine and uridine nucleoside analogs such as 6- azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)- acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine (PubMed:11306702). |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Uridine/cytidine kinase-1 (EC 2.7.1.48) is a pyrimidine ribonucleoside kinase that catalyzes the phosphorylation of uridine and cytidine to form uridine monophosphate (UMP) and cytidine monophosphate (CMP) (Van Rompay et al., 2001 [PubMed 11306702]).
References
Virovic Jukic, L., et al. J. Biomed. Sci. 15(2):205-213(2008)
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Van Rompay, A.R., et al. Mol. Pharmacol. 59(5):1181-1186(2001)
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