NAT15 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9H7X0 |
Other Accession | NP_001077069.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27451 Da |
Antigen Region | 133-160 aa |
Gene ID | 79903 |
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Other Names | N-alpha-acetyltransferase 60, Histone acetyltransferase type B protein 4, HAT4, N-acetyltransferase 15, NatF catalytic subunit, NAA60, HAT4, NAT15 |
Target/Specificity | This NAT15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the Central region of human NAT15. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NAT15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NAA60 {ECO:0000303|PubMed:25732826, ECO:0000312|HGNC:HGNC:25875} |
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Function | N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol (PubMed:25732826). Displays N-terminal acetyltransferase activity towards a range of N- terminal sequences including those starting with Met-Lys, Met-Val, Met- Ala and Met-Met (PubMed:21750686, PubMed:25732826, PubMed:27550639, PubMed:27320834). Required for normal chromosomal segregation during anaphase (PubMed:21750686). May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences (PubMed:21981917). |
Cellular Location | Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably forms an intramembrane hairpin-like structure in the membrane. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable N-acetyltransferase (By similarity).
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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