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STAC Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q99469 |
| Other Accession | A0JNJ1, NP_003140.1 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44554 Da |
| Antigen Region | 279-305 aa |
| Gene ID | 6769 |
|---|---|
| Other Names | SH3 and cysteine-rich domain-containing protein, Src homology 3 and cysteine-rich domain-containing protein, STAC |
| Target/Specificity | This STAC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-305 amino acids from the C-terminal region of human STAC. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | STAC Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STAC |
|---|---|
| Synonyms | STAC1 {ECO:0000303|PubMed:29078335} |
| Function | Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C. |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P97306}. Cell membrane {ECO:0000250|UniProtKB:P97306}; Peripheral membrane protein {ECO:0000250|UniProtKB:P97306}; Cytoplasmic side {ECO:0000250|UniProtKB:P97306}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P97306}; Peripheral membrane protein {ECO:0000250|UniProtKB:P97306}; Cytoplasmic side {ECO:0000250|UniProtKB:P97306} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
STAC is probably involved in a neuron-specific signal transduction.
References
Petek, E., et al. Cytogenet. Cell Genet. 84 (3-4), 184-185 (1999) :
Suzuki, H., et al. Biochem. Biophys. Res. Commun. 229(3):902-909(1996)
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