GDPD2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9HCC8 |
Other Accession | NP_060181.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 61729 Da |
Antigen Region | 305-334 aa |
Gene ID | 54857 |
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Other Names | Glycerophosphoinositol inositolphosphodiesterase GDPD2, Glycerophosphodiester phosphodiesterase 3, Glycerophosphodiester phosphodiesterase domain-containing protein 2, Osteoblast differentiation promoting factor, GDPD2, GDE3, OBDPF |
Target/Specificity | This GDPD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human GDPD2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GDPD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GDPD2 |
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Synonyms | GDE3, OBDPF |
Function | Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with the actin cytoskeleton. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants.
References
Corda, D., et al. J. Biol. Chem. 284(37):24848-24856(2009)
Yanaka, N., et al. J. Biol. Chem. 278(44):43595-43602(2003)
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