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GPR172B Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NWF4 |
| Other Accession | NP_001098047.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46317 Da |
| Antigen Region | 162-190 aa |
| Gene ID | 55065 |
|---|---|
| Other Names | Solute carrier family 52, riboflavin transporter, member 1, Porcine endogenous retrovirus A receptor 2, PERV-A receptor 2, Protein GPR172B, Riboflavin transporter 1, hRFT1, SLC52A1, GPR172B, PAR2, RFT1 |
| Target/Specificity | This GPR172B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human GPR172B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPR172B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC52A1 (HGNC:30225) |
|---|---|
| Synonyms | GPR172B, PAR2, RFT1 |
| Function | Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:18632736, PubMed:20463145). Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
GPCR41 (MIM 607882) and GPCR42 act as receptors for porcine endogenous retrovirus subgroup A (PERV-A).[supplied by OMIM].
References
Yonezawa, A., et al. Am. J. Physiol., Cell Physiol. 295 (3), C632-C641 (2008) :
Ericsson, T.A., et al. Proc. Natl. Acad. Sci. U.S.A. 100(11):6759-6764(2003)
Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) :
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