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ZNF488 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96MN9 |
| Other Accession | NP_694579.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36962 Da |
| Antigen Region | 149-175 aa |
| Gene ID | 118738 |
|---|---|
| Other Names | Zinc finger protein 488, ZNF488 |
| Target/Specificity | This ZNF488 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the Central region of human ZNF488. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZNF488 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZNF488 |
|---|---|
| Function | Transcriptional repressor. Plays a role in oligodendrocyte differentiation, together with OLIG2. Mediates Notch signaling- activated formation of oligodendrocyte precursors. Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q5HZG9}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
ZNF488 may be involved in transcriptional regulation.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
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