SFXN3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
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Primary Accession | Q9BWM7 |
Other Accession | NP_112233.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 35503 Da |
Antigen Region | 288-314 aa |
Gene ID | 81855 |
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Other Names | Sideroflexin-3, SFXN3 |
Target/Specificity | This SFXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-314 amino acids from the C-terminal region of human SFXN3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SFXN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SFXN3 {ECO:0000303|PubMed:30442778, ECO:0000312|HGNC:HGNC:16087} |
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Function | Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778). |
Cellular Location | Mitochondrion membrane {ECO:0000269|PubMed:30442778, ECO:0000269|Ref.4}; Multi-pass membrane protein |

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Provided below are standard protocols that you may find useful for product applications.
Background
Potential iron transporter.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)

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