TAAR9 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
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Primary Accession | Q96RI9 |
Other Accession | Q5QD04, NP_778227.3 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39016 Da |
Antigen Region | 229-255 aa |
Gene ID | 134860 |
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Other Names | Trace amine-associated receptor 9, TaR-9, Trace amine receptor 9, Trace amine receptor 3, TaR-3, TAAR9, TA3, TAR3, TRAR3 |
Target/Specificity | This TAAR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-255 amino acids from the C-terminal region of human TAAR9. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TAAR9 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TAAR9 (HGNC:20977) |
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Function | Olfactory receptor specific for trace amines, such as N,N- dimethylcyclohexylamine (DMCHA) and beta-phenylethylamine (beta-PEA) (By similarity). In contrast to mouse and rat orthologs, not activated by triethylamine, cadaverine (CAD) or spermidine (PubMed:34600890). Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors (By similarity). Trace amine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (By similarity). In mature olfactory sensory neurons, TAAR9 is coupled with GNAL/G(olf)G alpha protein and mediates activation of adenylate cyclase activity to activate cAMP signaling and eventually transmit odorant signals to achieve membrane depolarization (By similarity). In immature olfactory sensory neurons, TAAR9 is coupled with GNAS/G(s) G alpha proteins (By similarity). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q5QD04}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5QD04} |

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Provided below are standard protocols that you may find useful for product applications.
Background
TAAR9 is a member of a large family of rhodopsin G protein-coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
References
Muller, D.J., et al. J Psychiatr Res 44(9):598-604(2010)
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Liberles, S.D., et al. Nature 442(7103):645-650(2006)
Lindemann, L., et al. Genomics 85(3):372-385(2005)
Vanti, W.B., et al. Genomics 82(5):531-536(2003)

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