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ERMAP Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ERMAP Antibody (N-term) AP18539a
    ERMAP Antibody (N-term) (Cat. #AP18539a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ERMAP antibody detected the ERMAP protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q96PL5
Other Accession NP_001017922.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 52605 Da
Antigen Region 69-95 aa
Additional Information
Gene ID 114625
Other Names Erythroid membrane-associated protein, hERMAP, Radin blood group antigen, Scianna blood group antigen, ERMAP, RD, SC
Target/Specificity This ERMAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-95 amino acids from the N-terminal region of human ERMAP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsERMAP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERMAP
Synonyms RD, SC
Function Possible role as a cell-adhesion or receptor molecule of erythroid cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cytoplasm
Tissue Location Expressed in erythroid-enriched bone marrow (at protein level). Highly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene.

References

Fuchisawa, A., et al. Immunohematology 25(1):18-19(2009)
Lin, L.D., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16(2):328-332(2008)
Flegel, W.A., et al. Transfusion 45(12):1940-1944(2005)
Hue-Roye, K., et al. Transfusion 45(2):245-247(2005)
Yan, L., et al. Immunohematology 21(1):10-14(2005)

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$ 365.00
$ 140.00
Cat# AP18539a
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