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RAB5B Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P61020 |
| Other Accession | P61021, Q5ZHW4, NP_002859.1 |
| Reactivity | Human, Mouse |
| Predicted | Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 23707 Da |
| Antigen Region | 85-112 aa |
| Gene ID | 5869 |
|---|---|
| Other Names | Ras-related protein Rab-5B, RAB5B |
| Target/Specificity | This RAB5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the Central region of human RAB5B. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RAB5B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAB5B (HGNC:9784) |
|---|---|
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Note=Enriched in stage I melanosomes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Protein transport. Probably involved in vesicular traffic (By similarity).
References
Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
Chen, P.I., et al. J. Biol. Chem. 284(44):30328-30338(2009)
Shin, N., et al. Exp. Cell Res. 314(10):2055-2065(2008)
Hakonarson, H., et al. Diabetes 57(4):1143-1146(2008)
Hirota, Y., et al. Biochem. Biophys. Res. Commun. 364(1):40-47(2007)
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